By S. González-Moreno
This e-book reports present study in peritoneal malignant dissemination, from its pathogenesis and molecular mechanisms to the most recent medical trials. The publication covers the necessities of perioperative intraperitoneal chemotherapy and glossy histopathological evaluate of peritoneal floor malignancy. The book’s historic standpoint at the unfolding of latest wisdom issues the best way for destiny study. participants contain best specialists, between them the pioneers who gave beginning to this new period in oncology.
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Additional info for Advances in Peritoneal Surface Oncology (Recent Results in Cancer Research, Volume 169)
Much of the confusion is due to inconsistent terminology and the lack of large series in which predictive factors are accurately identified . Precise identification and classification of mucinous tumours of the appendix are important, as there is considerable variation in the potential to cause mucinous intraperitoneal disease. Whilst there is, therefore, an increasing burden on the pathologist to identify and classify these tumours appropriately, a significant confounding factor is the fact that there is a spectrum of mucinous tumours rather than rigid categories.
Thorough sampling and examination of the mucin are therefore essential to identify malignant cells within the mucin . Accepting that PP is usually caused by an appendiceal lesion, even in the presence of ovarian pathology, one must ensure exemplary examination of the appendix, even if macroscopically 'normal' . Thus, in any patient with mucinous ascites, the appendix should be removed at the time of surgery, even in the presence of an ovarian tumour . This should then be examined histologically in its entirety, as mucinous lesions may be microscopic or focal and areas of rupture may have sealed off and healed.
Benevolo M, Mottolese M, Cosimelli M et al. (1998) Diagnostic and prognostic value of peritoneal immunocytology in gastric cancer. J Clin Oncol 16:3406– 3411 33. Juhl H, Stritzel M, Wroblewski A et al. (1994) Immunocytological detection of micrometastatic cells: comparative evaluation of findings in the peritoneal cavity and the bone marrow of gastric, colorectal and pancreatic cancer patients. Int J Cancer 57:330–335 34. Asao T, Fukuda T, Yazawa S et al. (1991) Carcinoembryonic antigen levels in peritoneal washings can predict peritoneal recurrence after curative resection of gastric cancer.