By S.K. Malhotra
In accordance with the vast ambitions set for the serial book of Advances in Structural Biology, quantity 6 comprises exhaustive articles from specialists in assorted components of biomedical examine. the typical thread one of the a number of articles is their relevance to the purposes of telephone biology to human healthiness.
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Extra resources for Advances in Structural Biology, Volume 6 (Advances in Structural Biology)
55 Advances in Structural Biology, Volume 6, pages 41-64. Copyright 9 2000 by JAI Press Inc. All rights of reproduction in any form reserved. ISBN: 0-7623-0594-0 41 42 KAREN C. MCCOWEN and E. DALE ABEL VI. Mechanisms of Insulin Signaling Abnormalities . . . . . . . . . . . . . A. Tumor Necrosis Factor-~ . . . . . . . . . . . . . . . . . . . . B. Glucosamine . . . . . . . . . . . . . . . . . . . . . . . . . C.
I. 56 56 57 58 59 59 60 BACKGROUND Glucose homeostasis is maintained in vivo through a balance between glucose disposal in multiple tissues, glucose production by hepatocytes, and absorption via the small intestine. In mammalian cells, glucose crosses cell membranes by facilitated diffusion mediated by a family of closely related glucose transport proteins (Gluts). Glucose transport into cells is essential for survival. , skeletal muscle, adipose, and cardiac) by binding its receptor on the cell surface and activating a series of reactions that leads ultimately to glucose uptake by a specific transporter, Glut4.
1997, 15, 8, 2894-2904. H. The Association of Cytogenetic Technologists: Burbank, CA, 1994. H. " A Practical Approach. Volume 1. Constitutional Analysis; Oxford University Press: New York, 2nd 1992. ed. ; Hayner-Buchan. ; Muraca, EJ. Cancer 1997a, 79( 11), 2162-2170. J. Hum. Pathol. 1997b, 28(7), 827-33. D. Nature 1973, 234, 290-293. , Bernardi, G. Proc. Natl. Acad. Sci. A. 1992, 89, 49 ! 3--4917. A. , 1990, pp. 823-827. C. Hum. Genet. 1976, 31,293-307. ; Ried, T. Science 1996, 273, 494-497. ; Andre, M.